Pre-implantation genetic diagnosis (PGD or PIGD) refers to genetic profiling of embryos prior to implantation (as a form of embryo profiling), and sometimes even of oocytes prior to fertilization. Pre-implantation genetic diagnosis (PGD) enables people with an inheritable condition in their family to avoid passing it on to their children. It involves checking the genes and/or chromosomes of embryos created through IVF. PGD is considered in a similar fashion to prenatal diagnosis. When used to screen for a specific genetic disease, its main advantage is that it avoids selective pregnancy termination as the method makes it highly likely that the baby will be free of the disease under consideration. PGD thus is an adjunct to assisted reproductive technology, and requires in vitro fertilization (IVF) to obtain oocytes or embryos for evaluation.
The term preimplantation genetic screening (PGS) is used to denote procedures that do not look for a specific disease but use PGD techniques to identify embryos at risk. The PGD allows studying the DNA of eggs or embryos to select those that meet certain characteristics. It is useful when they are previous chromosomal or genetic disorders in the family and within the context of in vitro fertilization programs.
The procedures may also be called preimplantation genetic profiling to adapt to the fact that they are sometimes used on oocytes or embryos prior to implantation for other reasons than diagnosis or screening.
Who is it for ?
• Who have ended previous pregnancies because of a serious genetic condition
• Who already have a child with a serious genetic condition
• Who have family history of a serious genetic condition, or
• Who have family history of chromosome problems.
You could mail your query at info@curisglobal.com for an estimate and evaluation by the Specialist.